transcription factor (TF)

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Introduction

A typical transcription factor contains a specific DNA-binding domain that directly contacts DNA, a multimerization domain that allows the formation of homo- or heteromultimers, & a transcrip- tional activation domain (TAD).

More general terms

More specific terms

References

  1. Tjian R, Maniatis T. Transcriptional activation: a complex puzzle with few easy pieces. Cell. 1994 Apr 8;77(1):5-8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8156597
  2. Classification of transcription factors: http://www.gene-regulation.com/pub/databases/transfac/cl.html

Database