vascular endothelial zinc finger 1; zinc finger protein 161; transcription factor DB1 (VEZF1, DB1, ZNF161)

Function

• possible transcription factor
• specifically binds to the CT/GC-rich region of the IL-3 promoter & mediates Tax transactivation of IL-3
• interacts with ARHGAP22 (putative)

Structure

• belongs to the krueppel C2H2-type Zn+2-finger protein family
  • contains 6 C2H2-type Zn+2 fingers

Compartment

nucleus

Expression

• ubiquitously expressed
• highest levels in skeletal muscle & kidney

More general terms

• transcription factor (TF)
• DNA-binding protein
• C2H2 type zinc finger protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7716
• OMIM: https://mirror.omim.org/entry/606747
• UniProt: http://www.uniprot.org/uniprot/Q14119.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7716