transcriptional silencer (transcriptional repressor)

Introduction

transcription factor that represses or silences expression of a gene or genes

More general terms

• transcription factor (TF)

More specific terms

• achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1, ASCL3, HASH3, SGN1)
• arginine-glutamic acid dipeptide repeats protein (atrophin-1-like protein, atrophin-1-related protein, RERE, ARG, ARP, ATN1L, KIAA0458)
• aryl hydrocarbon receptor repressor (AhR repressor, AhRR, AHRR, KIAA1234)
• AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B, histone deacetylase complex subunit SAP180, 180 kD Sin3-associated polypeptide, Sin3-associated polypeptide p180, Retinoblastoma-binding protein 1-like 1, breast cance...
• Bcl-2-associated transcription factor 1 (Btf, BCLAF1, KIAA0164)
• BCL-6 corepressor (BCoR, KIAA1575)
• BCoR-like protein 1 (BCL6 corepressor-like protein 1, BCoR-L1, BCORL1)
• breast cancer metastasis-suppressor 1 (BRMS1)
• BTB/POZ domain-containing protein 14B; nucleus accumbens-1; NAC-1 (BTBD14B, NAC1, NACC1)
• C-myc promoter-binding protein (DENN domain-containing protein 4A, DENND4A, IRLB, MYCPBP)
• calsenilin; Kv channel-interacting protein 3; KChIP3; A-type K+ channel modulatory protein 3; DRE-antagonist modulator; DREAM (KCNIP3, CSEN, DREAM, KCHIP3)
• cartilage homeoprotein 1 (CART1, ALX1)
• CBF1-interacting corepressor; recepin (CIR, CIR1)
• CCR4-NOT transcription complex subunit 1 (negative regulator of transcription subunit 1 homolog, NOT1H, hNOT1, CCR4-associated factor 1, CNOT1, CDC39, KIAA1007, NOT1, AD-005)
• CCR4-NOT transcription complex subunit 4; CCR4-associated factor 4; E3 ubiquitin-protein ligase CNOT4; transcriptional repressor NOT4Hp (CNOT4, NOT4)
• cell division cycle-associated 7-like protein (protein JPO2, transcription factor RAM2, CDCA7L, HR1, JPO2 R1)
• cellular nucleic acid-binding protein; CNBP; zinc finger protein 9 (CNBP, RNF163, ZNF9)
• class B basic helix-loop-helix protein 3; bHLHB3; differentially expressed in chondrocytes protein 2; hDEC2; enhancer-of-split & hairy-related protein 1; SHARP-1 (BHLHB3, BHLHE41)
• Dr1-associated corepressor (Dr1-associated protein 1, negative cofactor 2 alpha, NC2 alpha, DRAP1)
• fer3-like protein (nephew of atonal 3, basic helix-loop-helix protein N-twist, neuronal twist, FERD3L, NATO3, NTWIST)
• Fez family zinc finger protein 1 (zinc finger protein 312B, FEZF1, FEZ, ZNF312B)
• Fez family zinc finger protein 2 (forebrain embryonic zinc finger-like protein 2, zinc finger protein Fez-like, zinc finger protein 312, FEZF2, FEZL, ZNF312, FKSG36)
• fibrinogen silencer-binding protein (FSBP)
• forkhead box protein S1; forkhead-like 18 protein; forkhead-related transcription factor 10; FREAC-10 (FOXS1 FKHL18 FREAC10)
• gamma-interferon-inducible protein 16; Ifi-16; interferon-inducible myeloid differentiation transcriptional activator (IFI16, IFNGIP1)
• hairy & enhancer of split-related protein HELT; HES/HEY-like transcription factor (HELT)
• hairy/enhancer-of-split related with YRPW motif 2 (cardiovascular helix-loop-helix factor 1, hairy & enhancer of split-related protein 2, HESR-2, hairy-related transcription factor 2, HES-related repressor protein 2, protein gridlock homolog, HEY2, CHF...
• hairy/enhancer-of-split related with YRPW motif-like protein (hHeyL, hairy-related transcription factor 3, hHRT3, HEYL HRT3)
• histone-lysine N-methyltransferase EZH1; ENX-2; enhancer of zeste homolog 1 (EZH1, KIAA0388)
• histone-lysine N-methyltransferase EZH2; ENX-1; enhancer of zeste homolog 2; lysine N-methyltransferase 6 (EZH2, KMT6)
• HMG box-containing protein 1 (HMG box transcription factor 1, high mobility group box transcription factor 1, HBP1)
• homeobox protein Nkx-3.2; Bagpipe homeobox protein homolog 1; homeobox protein NK-3 homolog B (NKX3-2, BAPX1, NKX3B)
• homeobox protein TGIF2; 5'-TG-3'-interacting factor 2; TGF-beta-induced transcription factor 2; TGFB-induced factor 2 (TGIF2)
• Id (inhibition of differentiation/DNA binding) helix loop helix protein
• interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1, IRF-2BP1, IRF2BP1)
• interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2, IRF-2BP2, IRF2BP2)
• Krueppel-like factor 10; EGR-alpha; transforming growth factor-beta-inducible early growth response protein 1; TGFB-inducible early growth response protein 1; TIEG-1 (KLF10, TIEG, TIEG1)
• Krueppel-like factor 11; transforming growth factor-beta-inducible early growth response protein 2; TGFB-inducible early growth response protein 2; TIEG-2 (KLF11, FKLF, TIEG2)
• Krueppel-like factor 12; transcriptional repressor AP-2rep (KLF12, AP2REP, HSPC122)
• ligand-dependent corepressor; LCoR; Mblk1-related protein 2 (LCOR, KIAA1795, MLR2)
• MAD protein; MAX dimerizer; MAX dimerization protein 1 (MXD1, MAD)
• Max dimerization protein 4; Max dimerizer 4; class C basic helix-loop-helix protein 12; bHLHc12; Max-associated protein 4; Max-interacting transcriptional repressor MAD4 (MXD4, BHLHC12, MAD4)
• Max-binding protein MNT (protein ROX, Myc antagonist MNT, MNT, ROX)
• Max-interacting transcriptional repressor MAD3 (Max-associated protein 3, MAX dimerization protein 3, Myx, MXD3, MAD3)
• mesoderm induction early response protein 1 (Mi-er1, hmi-er1, early response 1, Er1, MIER1, KIAA1610)
• mesoderm induction early response protein 2 (Mi-er2, MIER2, KIAA1193)
• mesoderm induction early response protein 3 (Mi-er3, MIER3)
• methyl-CpG-binding domain protein 3-like 1 (MBD3-like 1, MBD3L1, MBD3L)
• mSin3A corepressor complex
• Msx2-interacting protein (SPEN homolog, SMART/HDAC1-associated repressor protein, SPEN, KIAA0929, MINT, SHARP)
• musculin; activated B-cell factor 1; ABF-1; class A basic helix-loop-helix protein 22; bHLHa22 (MSC, ABF1, BHLHA22)
• Myb-related protein p42POP; partner of profilin (P42POP, MYPOP)
• myelin expression factor 2 (MyEF-2, MST156, MYEF2 KIAA1341)
• N-cor repressor complex
• NF-kappa-B-repressing factor; NFkB-repressing factor; protein ITBA4; transcription factor NRF (NKRF, ITBA4, NRF)
• NGFI-A-binding protein 1 (EGR-1-binding protein 1, transcriptional regulatory protein p54, NAB1)
• NGFI-A-binding protein 2; EGR-1-binding protein 2; melanoma-associated delayed early response protein; MADER protein (NAB2, MADER)
• nuclear factor interleukin-3 regulated protein (E4 promoter binding-protein 4, interleukin-3 promoter transcriptional activator, transcriptional activator NF-IL3A, interleukin-3 binding-protein 1, NFIL3, E4BP4, IL3BP1)
• nuclear receptor corepressor (N-COR)
• nuclear receptor-interacting factor 3; centromere protein R; CENP-R; beta-3-endonexin; integrin beta-3-binding protein (ITGB3BP, CENPR, NRIF3)
• nuclease-sensitive element-binding protein 1; Y-box-binding protein 1; Y-box transcription factor; YB-1; CCAAT-binding transcription factor I subunit A; CBF-A; enhancer factor I subunit A; EFI-A; DNA-binding protein B; DBPB (YBX1, NSEP1, YB1)
• paired amphipathic helix protein sin3a; murine yeast transcription repressor Sin3 homolog; transcriptional corepressor Sin3a; histone deacetylase complex subunit Sin3a (SIN3A, mSin3A)
• paired amphipathic helix protein sin3b; histone deacetylase complex subunit sin3b; transcriptional corepressor sin3b (SIN3B, KIAA0700, msin3B)
• penicillinase repressor
• PHD finger protein 12; PHD factor 1; Pf1 (PHF12, KIAA1523)
• poly(U)-binding-splicing factor PUF60 (60 kD poly(U)-binding-splicing factor, FUSE-binding protein-interacting repressor, FBP-interacting repressor, siah-binding protein 1, Siah-BP1, Ro-binding protein 1, RoBP1, PUF60, FIR, ROBPI, SIAHBP1)
• Polycomb group multiprotein BCOR complex (PcG BCOR complex)
• polycomb group RING finger protein 2; DNA-binding protein mel-18; RING finger protein 110; zinc finger protein 144 (PCGF2, MEL18, RNF110, ZNF144)
• polycomb group RING finger protein 6 (RING finger protein 134, Mel18 & Bmi1-like RING finger, PCGF6, MBLR, RNF134)
• POU domain, class 3, transcription factor 1; octamer-binding protein 6; Oct-6; octamer-binding transcription factor 6; OTF-6; POU domain transcription factor SCIP (POU3F1, OCT6, OTF6)
• PRKC apoptosis WT1 regulator protein; prostate apoptosis response 4 protein; par-4 (PAWR PAR4)
• prohibitin-2; B-cell receptor-associated protein BAP37; repressor of estrogen receptor activity; D-prohibitin (PHB2, REA, BAP)
• protein capicua homolog (CIC, KIAA0306)
• protein EMSY (EMSY, C11orf30, GL002)
• Protein strawberry notch homolog 2 (SBNO2, KIAA0963)
• RE1-silencing transcription factor (neural-restrictive silencer factor, X2 box repressor, REST, NRSF, XBR)
• REST corepressor 3 ( RCOR3, KIAA1343)
• SET & MYND domain-containing protein 1 (SMYD1)
• sin3 repressor complex
• something about silencing protein 10; disrupter of silencing SAS10; charged amino acid-rich leucine zipper 1 (CRLZ1, SAS10, UTP3)
• suppression of tumorigenicity protein 18 (zinc finger protein 387, ST18, KIAA0535, ZNF387)
• T-box transcription factor TBX3; T-box protein 3 (TBX3)
• THAP domain-containing protein 7 (THAP7)
• transcription factor 25 (nuclear localized protein 1, TCF25, KIAA1049, NULP1, FKSG26)
• transcription factor 9; GC-rich sequence DNA-binding factor; GCF; GC-rich sequence DNA-binding factor (TCF9, GCFC2, C2orf3)
• transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1, CRTR-1, Transcription factor LBP-9, TFCP2L1, CRTR1, LBP9)
• transcription factor E4F1 (E3 ubiquitin-protein ligase E4F1, E4F transcription factor 1, transcription factor E4F, p120E4F, p50E4F, E4F1, E4F)
• transcription factor HES-1; class B basic helix-loop-helix protein 39; bHLHb39; Hairy & enhancer of split 1; Hairy homolog; Hairy-like protein; hHL (HES1, BHLHB39, HL, HRY)
• transcription factor HES-2 (hairy & enhancer of split 2, HES2)
• transcription factor HES-3 (hairy & enhancer of split 3)
• transcription factor HES-5 (Hairy & enhancer of split 5, HES5)
• transcription factor HES-7 (hairy & enhancer of split 7, bHLH factor Hes7, HES7)
• transcriptional repressor CTCF; 11-zinc finger protein; CCCTC-binding factor; CTCFL paralog (CTCF)
• transcriptional repressor CTCFL (CCCTC-binding factor, Brother of the regulator of imprinted sites, zinc finger protein CTCF-T, CTCF paralog, CTCFL BORIS)
• transcriptional repressor NF-X1; nuclear transcription factor, X box-binding protein 1 (NFX1, NFX2)
• transcriptional repressor p66 alpha (Hp66alpha, GATA zinc finger domain-containing protein 2A, GATAD2A)
• transcriptional repressor protein YY1; Yin & yang 1; YY-1; delta transcription factor; NF-E1 (YY1)
• transcriptional repressor scratch 1; Scratch homolog 1 zinc finger protein; SCRT; Scratch 1; hScrt (SCRT1)
• transcriptional repressor scratch 2; Scratch homolog 2 zinc finger protein (SCRT2)
• transducin-like enhancer protein 6 (TLE6)
• TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2, Tsc-22-like protein THG-1, TSC22D4, TILZ2)
• YY1-associated factor 2 (YAF2)
• zinc finger & BTB domain-containing protein 23; zinc finger protein 336; GDNF-inducible zinc finger protein 1 (GZF1, ZBTB23, ZNF336)
• zinc finger protein 133; zinc finger protein 150 (ZNF133, ZNF150)
• zinc finger protein 136 (ZNF136)
• zinc finger protein 138 (ZNF138)
• zinc finger protein 140 (ZNF140)
• zinc finger protein 141 (ZNF141, D4S90)
• zinc finger protein 148; zinc finger DNA-binding protein 89; transcription factor ZBP-89 (ZNF148, ZBP89)
• zinc finger protein 161 homolog; Zfp-161; zinc finger protein 5; HZF5; zinc finger & BTB domain-containing protein 14 (ZFP161, ZBTB14)
• zinc finger protein 174; AW-1; zinc finger & SCAN domain-containing protein 8 (ZNF174, ZSCAN8)
• zinc finger protein 202; zinc finger protein with KRAB & SCAN domains 10 (ZNF202, ZKSCAN10)
• zinc finger protein 238; 58 kD repressor protein; transcriptional repressor RP58; translin-associated zinc finger protein 1; TAZ-1; zinc finger & BTB domain-containing protein 18; zinc finger protein C2H2-171 (ZNF238, RP58, TAZ1, ZBTB18)
• zinc finger protein 274; neurotrophin receptor-interacting factor homolog; zinc finger protein HFB101; zinc finger protein with KRAB & SCAN domains 19; zinc finger protein zfp2; Zf2 (ZNF274, ZKSCAN19, SP2114)
• zinc finger protein 281; GC-box-binding zinc finger protein 1; transcription factor ZBP-99; zinc finger DNA-binding protein 99 (ZNF281, GZP1, ZBP99)
• zinc finger protein 282; HTLV-I U5RE-binding protein 1; HUB-1 (ZNF282 HUB1)
• zinc finger protein 300 (ZNF300)
• zinc finger protein 328; zinc finger protein 606 (ZNF606, KIAA1852, ZNF328)
• zinc finger protein 354C; kidney, ischemia, & developmentally-regulated protein 3; hKID3 (ZNF354C, KID3)
• zinc finger protein 366 (ZNF366)
• zinc finger protein 382; KRAB/zinc finger suppressor protein 1; KS1; multiple zinc finger & krueppel-associated box protein KS1 (ZNF382)
• zinc finger protein 396; zinc finger & SCAN domain-containing protein 14 (ZNF396, ZSCAN14)
• zinc finger protein 503 (ZNF503)
• zinc finger protein 57 homolog (Zfp-57, zinc finger protein 698, ZFP57, C6orf40, ZNF698)
• zinc finger protein 85; zinc finger protein HPF4; HTF1 (ZNF85)
• zinc finger protein Eos; Ikaros family Zn+2 finger protein 4 (IKZF4, KIAA1782, ZNFN1A4, zinc finger protein-1A-4 )
• zinc finger protein Gfi-1; growth factor independent protein 1; zinc finger protein 163 (GFI1, ZNF163)
• zinc finger protein SNAI3 (protein snail homolog 3, zinc finger protein 293) (SNAI3 ZNF293)