zinc finger protein SNAI3 (protein snail homolog 3, zinc finger protein 293) (SNAI3 ZNF293)

Function

• seems to inhibit myoblast differentiation
• transcriptional repressor of E-box-dependent transactivation of downstream myogenic bHLHs genes
• binds preferentially to the canonical E-box sequences 5'-CAGGTG-3' & 5'-CACCTG-3'

Structure

• binds E-box via C2H2-type Zn+2-finger domain
• belongs to the snail C2H2-type Zn+2-finger protein family
• contains 5 <A144105>C2H2-type Zn+2-fingers</A144105>

Compartment

nucleus (putative)

More general terms

• transcriptional silencer (transcriptional repressor)
• C2H2 type zinc finger protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3339
• UniProt: http://www.uniprot.org/uniprot/Q3KNW1.html