polycomb group RING finger protein 6 (RING finger protein 134, Mel18 & Bmi1-like RING finger, PCGF6, MBLR, RNF134)

Function

• transcriptional repressor
• interacts with PCGF4, RING1, RNF2
• phosphorylated during mitosis

Structure

• contains 1 RING-type zinc finger

Compartment

nucleus

Alternative splicing

named isoforms=3

Expression

ubiquitous

Polymorphism

• poly-Pro stretch (P24-P28) may be polymorphic, varies from 5-7 Pro residues

More general terms

• ring finger protein
• transcriptional silencer (transcriptional repressor)
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/607816
• UniProt: http://www.uniprot.org/uniprot/Q9BYE7.html