SET & MYND domain-containing protein 1 (SMYD1)

Function

• transcriptional repressor
• essential for cardiomyocyte differentiation & cardiac morphogenesis
• interacts with HDAC1, HDAC2 & HDAC3

Structure

• contains 1 MYND-type zinc finger
• contains 1 SET domain

Compartment

cytoplasm, nucleus

More general terms

• transcriptional silencer (transcriptional repressor)
• SET & MYND domain-containing protein (SMYD)

Database

• OMIM: https://mirror.omim.org/entry/606846
• UniProt: http://www.uniprot.org/uniprot/Q8NB12.html