transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1, CRTR-1, Transcription factor LBP-9, TFCP2L1, CRTR1, LBP9)

Function

• transcriptional suppressor
• may suppress UBP1-mediated transcriptional activation
• modulates placental expression of CYP11A1

Structure

belongs to the grh/CP2 family. CP2 subfamily

Compartment

nucleus

Expression

• highly expressed in placental JEG-3 cells
• very low levels of expression in non-steroidogenic cells
• no expression was seen in adrenal NCI-H295A cells or in adrenal tissue

More general terms

• transcriptional silencer (transcriptional repressor)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9NZI6.html