Fez family zinc finger protein 1 (zinc finger protein 312B, FEZF1, FEZ, ZNF312B)

Function

• transcription repressor
• role in axonal projection proper termination of olfactory sensory neurons
• role in rostro-caudal patterning of diencephalon & in prethalamic formation
• regulates layer formation in olfactory bulb development and the interneuron
• may be required for correct rostral migration of interneuron progenitors in olfactory bulb

Structure

• belongs to the krueppel C2H2-type zinc-finger protein family
• contains 6 C2H2-type zinc fingers

Compartment

nucleus

Alternative splicing

named isoforms=3

More general terms

• C2H2 type zinc finger protein
• transcriptional silencer (transcriptional repressor)

Database

• UniProt: http://www.uniprot.org/uniprot/A0PJY2.html