zinc finger protein 396; zinc finger & SCAN domain-containing protein 14 (ZNF396, ZSCAN14)

Function

• isoforms 1 & 2 act as DNA-dependent transcriptional repressors
• isoforms 1 & 2 can for homodimers or heterodimers

Structure

• belongs to the krueppel C2H2-type Zn+2-finger protein family
• contains 3 C2H2-type Zn+2 fingers
• contains 1 SCAN box domain

Compartment

• isoform 1: nucleus
• isoform 2: nucleus, cytoplasm

Alternative splicing

named isoforms=3

Expression

• expressed in liver > skeletal muscle > kidney, pancreas, spleen, prostate

More general terms

• C2H2 type zinc finger protein
• transcriptional silencer (transcriptional repressor)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=252884
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:252884
• OMIM: https://mirror.omim.org/entry/609600
• UniProt: http://www.uniprot.org/uniprot/Q96N95.html