zinc finger protein 136 (ZNF136)

Function

• role as weak transcriptional repressor alone, or a potent one when fused with a heterologous protein containing a KRAB B-domain (putative)

Structure

• belongs to the krueppel C2H2-type Zn+2-finger protein family
• contains 14 C2H2-type Zn+2 fingers
• contains 1 KRAB domain

Compartment

nucleus (putative)

Expression

• seems ubiquitous
• expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney & pancreas

More general terms

• transcriptional silencer (transcriptional repressor)
• C2H2 type zinc finger protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7695
• OMIM: https://mirror.omim.org/entry/604078
• UniProt: http://www.uniprot.org/uniprot/P52737.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7695