zinc finger protein 300 (ZNF300)

Function

• has transcriptional repressor activity

Structure

• belongs to the krueppel C2H2-type Zn+2-finger protein family
• contains 12 C2H2-type Zn+2 fingers
• contains 1 KRAB domain

Compartment

nucleus

Alternative splicing

named isoforms=3

Expression

• expressed mostly in heart, skeletal muscle & brain
• isoform 1 & isoform 2 are highly expressed in testis

More general terms

• zinc finger protein
• transcriptional silencer (transcriptional repressor)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=91975
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:91975
• OMIM: https://mirror.omim.org/entry/612429
• UniProt: http://www.uniprot.org/uniprot/Q96RE9.html