transcription factor 25 (nuclear localized protein 1, TCF25, KIAA1049, NULP1, FKSG26)

Function

• transcriptional repressor
• can repress transcription of SRF in vitro
• role in heart development (putative)

Structure

• C-terminal region mediates transcriptional repression
• belongs to the NULP1 family

Compartment

nucleus

Expression

• in the embryo, widely expressed with highest levels in brain
• in the adult, highest expression is found in the heart

More general terms

• transcriptional silencer (transcriptional repressor)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9BQ70.html