zinc finger protein 174; AW-1; zinc finger & SCAN domain-containing protein 8 (ZNF174, ZSCAN8)

Function

transcriptional repressor

Structure

• belongs to the krueppel C2H2-type Zn+2-finger protein family
• contains 3 C2H2-type Zn+2 fingers
• contains 1 SCAN box domain

Compartment

nucleus

Alternative splicing

named isoforms=2

Expression

• expressed in a variety of organs
• expressed in adult testis & ovary > small intestine, colon, prostate, thymus, spleen, pancreas, skeletal muscle, heart, brain & kidney
• also expressed in umbilical vein endothelial cells, foreskin fibroblast & HEPG2 cells

More general terms

• phosphoprotein
• transcriptional silencer (transcriptional repressor)
• C2H2 type zinc finger protein
• zinc finger & SCAN domain-containing protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7727
• OMIM: https://mirror.omim.org/entry/603900
• UniProt: http://www.uniprot.org/uniprot/Q15697.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7727