transcription factor 9; GC-rich sequence DNA-binding factor; GCF; GC-rich sequence DNA-binding factor (TCF9, GCFC2, C2orf3)

Function

• factor that represses transcription
• binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, & Ca+2-dependent protease promoters

Structure

belongs to the GCF family

Compartment

nucleus

Alternative splicing

named isoforms=2

Expression

widely expressed in tissues & cell lines

More general terms

• transcriptional silencer (transcriptional repressor)
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P16383.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6936
• OMIM: https://mirror.omim.org/entry/189901