mediator of RNA polymerase II transcription subunit 13; activator-recruited cofactor 250 kD component; ARC250; mediator complex subunit 13; thyroid hormone receptor-associated protein 1; thyroid hormone receptor-associated protein complex 240 kD component; trap240; vitamin D3 receptor-interacting protein complex component DRIP250; DRIP250 (MED13, ARC250, KIAA0593, THRAP1, TRAP240)

Function

• component of the mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase 2- dependent genes

Structure

• belongs to the mediator complex subunit 13 family

Compartment

nucleus

Expression

ubiquitous

More general terms

• transcription factor (TF)
• phosphoprotein

Component of

• thyroid hormone receptor associated protein complex (TRAP)
• activator-recruited cofactor (ARC)/DRIP
• mediator complex (mediator of RNA polymerase 2 transcription)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9969
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9969
• OMIM: https://mirror.omim.org/entry/603808
• UniProt: http://www.uniprot.org/uniprot/Q9UHV7.html