AF4 protein; ALL1-fused gene product from chromosome 4; AF4/FMR2 family member 1; proto-oncogene protein AF4; FEL protein (AFF1, AF4, FEL, MLLT2)

Compartment

nucleus

Pathology

• chromosomal translocation t(4;11)(q21;q23) with MLL is associated with acute leukeuma; the result is a rogue activator protein

More general terms

• transcription factor (TF)
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/159557
• UniProt: http://www.uniprot.org/uniprot/P51825.html