transcription factor LBX1; ladybird homeobox protein homolog 1 (LBX1, LBX1H)

Function

• transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord & migration & further development of hypaxial muscle precursor cells for limb muscles, diaphragm & hypoglossal cord
• interacts with SKOR1 which acts as a transcriptional corepressor (putative)

Structure

• contains 1 homeobox DNA-binding domain

Compartment

nucleus (probable)

More general terms

• transcription factor (TF)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10660
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10660
• OMIM: https://mirror.omim.org/entry/604255
• UniProt: http://www.uniprot.org/uniprot/P52954.html