undifferentiated embryonic cell transcription factor 1 (UTF1)

Function

• acts as a transcriptional coactivator of ATF2
• binds to the N-terminal region of ATF2
• associates with the TFIID complex through interaction with TBP
• leucine-zipper domain required for coactivation activity, when deleted, UTF1 is able to stimulate transcription from a number of gene promoters
• phosphorylated

Compartment

nucleus

More general terms

• transcription factor (TF)

Database

• OMIM: https://mirror.omim.org/entry/604130
• UniProt: http://www.uniprot.org/uniprot/Q5T230.html