cell differentiation protein RCD1 homolog (Rcd-1, RQCD1, RCD1)

Function

• transcription factor that down-regulates MYB- & JUN-dependent transcription
• may play a role in cell differentiation (putative)
• can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain
• does not bind poly-A
• interacts with MYB, ATF2, RARA, RARB, RARG, RXRA, RXRB & RXRG
• identified in a complex with ATF2 bound to target DNA (putative). homodimer

Structure

• homodimer
• belongs to the RCD1 family

Compartment

nucleus (putative)

Expression

• detected in spleen, thymus, prostate, testis, ovary & intestine

More general terms

• transcription factor (TF)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9125
• UniProt: http://www.uniprot.org/uniprot/Q92600.html