retinoic acid receptor RXR-beta; retinoid X receptor beta; nuclear receptor subfamily 2 group B member 2 (RXRB, NR2B2)

From Aaushi

Jump to navigation Jump to search

^[1]^[2]^[3]

Function

nuclear hormone receptor
role in retinoic acid response pathway
binds 9-cis retinoic acid (9C-RA)

Structure

composed of three domains:
- modulating N-terminal domain
- DNA-binding domain
- C-terminal steroid-binding domain
belongs to the nuclear hormone receptor family, NR2 subfamily
contains 1 nuclear receptor DNA-binding domain

Compartment

Expression

expressed in a variety of tumor cell lines

More general terms

retinoid X receptor (RXR)

References

↑ Sporn MB, Roberts AB. Interactions of retinoids and transforming growth factor-beta in regulation of cell differentiation and proliferation. Mol Endocrinol. 1991 Jan;5(1):3-7. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2017191
↑ Green S. Nuclear hormone receptors. Promiscuous liaisons. Nature. 1993 Feb 18;361(6413):590-1. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8382343
↑ UniProt http://www.uniprot.org/uniprot/P28702.html

Database

Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6257
OMIM: https://mirror.omim.org/entry/180246
UniProt: http://www.uniprot.org/uniprot/P28702.html
Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6257

Retrieved from "https://aaushi.info/w/index.php?title=A126144&oldid=1032621"

↑ Back to top