transcriptional activator protein Pur-alpha (purine-rich single-stranded DNA-binding protein alpha, PURA, PUR1)

Function

• transcription activator (putative)
• binds purine-rich single strand of the PUR element located upstream of the MYC gene
• initiation of DNA replication
• recombination
• homodimer, heterodimer with PURB & heterotrimer with PURB & YBX1/Y-box protein 1
• antagonizes action of MYEF2

Compartment

nucleus

More general terms

• transcription factor (TF)

Database

• OMIM: https://mirror.omim.org/entry/600473
• UniProt: http://www.uniprot.org/uniprot/Q00577.html