zinc finger protein 8; zinc finger protein HF.18 (ZNF8)

Function

• may be involved in transcriptional regulation
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• belongs to the krueppel C2H2-type Zn+2-finger protein family
• contains 7 C2H2-type Zn+2 fingers
• contains 1 KRAB domain

Compartment

nucleus (probable)

Expression

• ubiquitously present in many human cell lines of different embryological derivation

More general terms

• transcription factor (TF)
• C2H2 type zinc finger protein
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/194532
• UniProt: http://www.uniprot.org/uniprot/P17098.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7554