ATM protein (Ataxia Telangiectasia mutated)

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Introduction

Protein product of gene mutated in ataxia telangiectasia

Function

ATP + a protein = ADP + a phosphoprotein

Inhibited by wortmannin

Structure

Compartment

Expression

Pathology

More general terms

Additional terms

Component of

References

  1. Lavin MF, Khanna KK, Beamish H, Spring K, Watters D, Shiloh Y. Relationship of the ataxia-telangiectasia protein ATM to phosphoinositide 3-kinase. Trends Biochem Sci. 1995 Oct;20(10):382-3. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8533147
  2. Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=472
  3. Uniprot :accession
  4. Ataxia talangiectasia mutation db http://benaroyaresearch.org/investigators/concannon_patrick/atm.htm
  5. Atlas of Genetics and Cytogenetics in Oncology and Haematology http://atlasgeneticsoncology.org/Genes/ATM123.html
  6. GeneReviews https://www.genecards.org/cgi-bin/carddisp.pl?gene=ATM
  7. Wikipedia ataxia telangiectasia mutated entry http://en.wikipedia.org/wiki/Ataxia_telangiectasia_mutated

Database