apoptosis

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Origin

  • apoptosis is from the Greek apo meaning 'from' & ptosis meaning 'a fall'
  • the term apoptosis was originally used to describe the cell death that occurred outside the zone of central necrosis resulting from ligation of the portal vein

Pathology

* see figure caspase signaling, see figure PI-3 kinase

Physiology

Laboratory

* image of myeloblast apoptosis[5]

More general terms

More specific terms

Additional terms

References

  1. 1.0 1.1 Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science. 1995 Mar 10;267(5203):1456-62. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7878464
  2. Sedlak TW, Snyder SH. Messenger molecules and cell death: therapeutic implications. JAMA. 2006 Jan 4;295(1):81-9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16391220
  3. Okada H, Mak TW. Pathways of apoptotic and non-apoptotic death in tumour cells. Nat Rev Cancer. 2004 Aug;4(8):592-603. Review. No abstract available. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15286739
  4. Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell. 2004 Jan 23;116(2):205-19. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/14744432
  5. 5.0 5.1 Markewitz RDH, Dargvainiene J Images in Clinical Medicine Mitotic and Apoptotic Figures on a Peripheral-Blood Smear. N Engl J Med. 2021. May 15 PMID: https://www.ncbi.nlm.nih.gov/pubmed/34014049 https://www.nejm.org/doi/full/10.1056/NEJMicm2033085

Database