cytokine receptor

Introduction

This superfamily of receptors conveys their signals through interactions with Janus kinases. Binding of cytokine to receptor induces oligomerization of receptor & enhances affinity of cyto- plasmic domain for Janus kinase. Cytokine receptors may also directly stimulate src family of tyrosine kinases.

More general terms

• cell surface receptor
• metabotropic receptor
• phosphoprotein

More specific terms

• AI2CA
• AI2CB
• CDw119; interferon-gamma receptor alpha chain; IFN-gamma-R1; CD119 (IFNGR1)
• CDw131; cytokine receptor common subunit beta; KH97; GM-CSF/IL-3/IL-5 receptor common beta-chain; CDw131; CD131 (CSF2RB, IL3RB, IL5RB)
• chemokine receptor (chemoattractant receptor)
• ciliary neurotrophic factor [CNTF] receptor
• colony-stimulating factor [CSF] receptor
• erythropoietin receptor; EPO-R (EPOR)
• interferon receptor
• interleukin receptor
• leptin receptor; LEP-R; OB receptor; OB-R; HuB219; CD295 (LEPR, DB, OBR)
• leukemia inhibitory factor [LIF] receptor or oncostatin M [Osm] receptor
• tgf beta receptor superfamily
• thrombopoietin receptor; TPO-R; myeloproliferative leukemia protein; C-mpl; CD110 (MPL, TPOR)
• transforming growth factor [TGF] receptor

Additional terms

• cytokine

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?