cytokine
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Introduction
Cytokines are secreted peptides/proteins functioning as intercellular messengers. Cytokines may be distinguished from classical hormones in several ways. The are normally made by more than one cell, have a wide range of overlapping biological activities, & generally act over a short range. Most mammalian cells seem to be able to produce a range of cytokines & to respond to various cytokines through surface receptors.
More general terms
More specific terms
- adipokine
- bone morphogenetic protein (BMP)
- chemokine; chemoattractant
- chemotactic cytokine CP10
- ciliary neurotrophic factor; CNTF (CNTF)
- embryonic growth/differentiation factor 1; GDF-1 (GDF1)
- epidermal growth factor (EGF)/urogastrone
- fibroblast growth factor
- G26 T-cell secreted protein
- gremlin-1 (cysteine knot superfamily 1 BMP antagonist 1, increased in high glucose protein 2, IHG-2, down-regulated in Mos-transformed cells protein, proliferation-inducing gene 2 protein, GREM1, CKTSF1B1, DAND2, DRM, PIG2)
- gremlin-2 (cysteine knot superfamily 1 BMP antagonist 2, protein related to DAN & cerberus, GREM2, CKTSF1B2, DAND3, PRDC)
- hematopoietic cell growth factor
- IL-1 receptor accessory protein (IL-1 receptor accessory protein, IL-1RAcP, IL1RAP)
- interferon
- interleukin
- interleukin-1 receptor antagonist protein; IL-1ra; IL-1RN; IRAP; IL1 inhibitor; ICIL-1RA (IL1RN, IL1F3, IL1RA)
- leukemia inhibitory factor; melanoma-derived LPL inhibitor; differentiation-stimulating factor; D factor,; HILDA; MLPLI; emfilermin (LIF)
- leukocyte cell derived chemotaxin (lect)
- lymphokine
- macrophage migration inhibitory factor; MIF; glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase; phenylpyruvate tautomerase (MIF, GLIF, MMIF)
- monokine
- neuropoietin
- nodal homolog (NODAL)
- oncostatin-M (OSM)
- platelet-derived growth factor (PDGF)
- sis-epsilon or p500
- stem cell factor; mast-cell growth factor; c-kit ligand; steel homolog (SCF, KITLG, MGF)
- thrombopoietin; megakaryocyte colony stimulating factor; C-MPL ligand; megakaryocyte growth & development factor (MGDF, THPO)
- transforming growth factor [TGF]-beta
- tumor necrosis factor (TNF) family protein
Additional terms
References
- ↑ Henderson & Bake TIPS 13:145 1993
- ↑ Schaible HG, von Banchet GS, Boettger MK et al The role of proinflammatory cytokines in the generation and maintenance of joint pain. Ann N Y Acad Sci. 2010 Apr;1193:60-9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20398009