nodal homolog (NODAL)

Function

• essential for mesoderm formation & axial patterning during embryonic development (putative)

Structure

• homodimer; disulfide-linked (putative)
• belongs to the TGF-beta family

Compartment

secreted (putative)

Pathology

• defects in NODAL are the cause of visceral heterotaxy autosomal type 5

More general terms

• cytokine
• glycoprotein
• TGF-beta family protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4838
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4838
• OMIM: https://mirror.omim.org/entry/270100
• OMIM: https://mirror.omim.org/entry/601265
• UniProt: http://www.uniprot.org/uniprot/Q96S42.html