tumor necrosis factor (TNF) family protein

Introduction

Cytotoxic for tumor cells. T cell growth & differentiation, induction of adhesion molecules. Fever induction, Activation of endothelial cells.

More general terms

• cytokine

More specific terms

• tumor necrosis factor ligand superfamily member 8; CD153; CD30 ligand; CD30-L (TNFSF8, CD30L, CD30LG)
• tumor necrosis factor ligand superfamily member 5 (TNFSF5), CD154, CD40 ligand (CD40L), T-cell antigen gp39, TNF-related activation protein (TRAP) or T-BAM
• CD253; tumor necrosis factor ligand superfamily member 10; apo-2 ligand; apo-2L; TNF-related apoptosis-inducing ligand; protein TRAIL (TNFSF10, APO2L, TRAIL)
• tumor necrosis factor ligand superfamily member 7; CD70; CD27L (TNFSF7)
• tumor necrosis factor ligand superfamily member 6; Fas ligand; Fas antigen ligand; CD95L protein; apoptosis antigen ligand; APTL; CD178 (FASLG, APT1LG1, FASL, TNFSF6)
• lymphotoxin-alpha; LT-alpha; TNF-beta; tumor necrosis factor ligand superfamily member 1 (LTA, TNFB, TNFSF1)
• lymphotoxin-beta; LT-beta; tumor necrosis factor C; TNF-C; tumor necrosis factor ligand superfamily member 3 (LTB, TNFC, TNFSF3)
• tumor necrosis factor ligand superfamily member 11; osteoclast differentiation factor; ODF; osteoprotegerin ligand; OPGL; receptor activator of nuclear factor kappa-B ligand; RANKL; TNF-related activation-induced cytokine; TRANCE; CD254; contains: tum...
• tumor necrosis factor ligand superfamily member 12; TNF-related weak inducer of apoptosis; TWEAK; APO3 ligand (TNFSF12, APO3L, DR3LG, UNQ181/PRO207)
• tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand; APRIL; TNF- & APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; CD256 (TNFSF13, APRIL, TALL2, ZTNF2, UNQ383/PRO715)
• tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; dendritic cell-derived TNF-like molecule; TNF- & APOL-related leukocyte expressed ligand 1; TALL-1; CD257 (TNFSF13B, BAFF, BLYS, TALL1, ...
• tumor necrosis factor ligand superfamily member 14; Herpes virus entry mediator ligand; HVEM-L; CD258 (TNFSF14, HVEML, LIGHT, UNQ391/PRO726)
• tumor necrosis factor ligand superfamily member 15; TNF ligand-related molecule 1; vascular endothelial cell growth inhibitor (TNFSF15, TL1, VEGI)
• tumor necrosis factor ligand superfamily member 18; activation-inducible TNF-related ligand; AITRL; glucocorticoid-induced TNF-related ligand; hGITRL (TNFSF18, AITRL, GITRL, TL6, UNQ149/PRO175)
• tumor necrosis factor ligand superfamily member 4; OX40 ligand; OX40L; glycoprotein Gp34; TAX transcriptionally-activated glycoprotein 1; CD252 (TNFSF4, TXGP1)
• tumor necrosis factor ligand superfamily member 9; 4-1BB ligand; 4-1BBL (TNFSF9)
• tumor necrosis factor [TNF]-alpha; tumor necrosis factor ligand superfamily member 2; cachectin (TNF, TNFA, TNFSF2)