ciliary neurotrophic factor; CNTF (CNTF)

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Function

CNTF is produced by Schwann cells in response to peripheral nerve injury & is transported anterogradely to the neuronal cell body
CNTF lacks a classical peptide signal sequence for the secretory pathway & is probably released following cell disruption

Structure

belongs to the CNTF family

Compartment

Expression

produced by Schwann cells

More general terms

References

↑ Hopkins SJ & Rothwell NJ Cytokines and the nervous system. I: Expression and recognition. TINS 18:83 1995 PMID: https://www.ncbi.nlm.nih.gov/pubmed/7537419
↑ UniProt http://www.uniprot.org/uniprot/P26441.html
↑ Wikipedia; Note: ciliary neurotrophic factor entry http://en.wikipedia.org/wiki/ciliary_neurotrophic_factor

Database

Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1270
Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1270
OMIM: https://mirror.omim.org/entry/118945
UniProt: http://www.uniprot.org/uniprot/P26441.html

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