platelet-derived growth factor (PDGF)
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Function
- PDGF stimulates tyrosine phosphorylation of the focal adhesion kinase (FAK) & paxillin & induces the association of PI-3-kinase with FAK[2]
More general terms
More specific terms
- platelet-derived growth factor alpha/beta; PDGF-alpha/beta (PDGFA/PDGFB)
- platelet-derived growth factor D (PDGF D, iris-expressed growth factor, spinal cord-derived growth factor B, SCDGF-B, PDGFD, IEGF, SCDGFB, MSTP036, UNQ1899/PRO4345)
- platelet-derived growth factor subunit A; PDGF subunit A; PDGF-1; platelet-derived growth factor A chain; platelet-derived growth factor alpha polypeptide (PDGFA, PDGF1)
- platelet-derived growth factor subunit B; PDGF subunit B; PDGF-2; platelet-derived growth factor B chain; platelet-derived growth factor beta polypeptide; proto-oncogene c-sis; Becaplermin (PDGFB, PDGF2, SIS)
Additional terms
References
- ↑ Hajjar DP & Pomerantz KB Signal transduction in atherosclerosis: integration of cytokines and the eicosanoid network. FASEB J 6:2933 1992 PMID: https://www.ncbi.nlm.nih.gov/pubmed/1644257
- ↑ 2.0 2.1 Clark EA & Brugge JS Integrins and signal transduction pathways: the road taken. Science 268:233 1995 PMID: https://www.ncbi.nlm.nih.gov/pubmed/7716514