platelet-derived growth factor subunit A; PDGF subunit A; PDGF-1; platelet-derived growth factor A chain; platelet-derived growth factor alpha polypeptide (PDGFA, PDGF1)

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Function

Structure

  • the long form contains a basic insert which acts as a cell retention signal
  • belongs to the PDGF/VEGF growth factor family

Compartment

Alternative splicing

named isoforms=2; long, short

Expression

platelets

More general terms

References

  1. UniProt http://www.uniprot.org/uniprot/P04085.html
  2. R&D systems' cytokine mini-reviews: PDGF http://www.rndsystems.com/molecule_detail.aspx?m=1967
  3. Matsui T et al, Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes Science 243:800 1989 PMID: https://www.ncbi.nlm.nih.gov/pubmed/2536956
  4. Henderson B & Blake S Therapeutic potential of cytokine manipulation TIPS 13:145 1992 PMID: https://www.ncbi.nlm.nih.gov/pubmed/1589908

Database