tyrosine kinase (protein tyrosine kinase, PTK)

Function

• protein tyrosine kinases do not occur in yeast, & as tyrosine kinases in eukaryotes seem to play a role in signal transduction, it is speculated that tyrosine kinases may have evolved to play a role in cell-cell communication

More general terms

• protein kinase

More specific terms

• abl protein
• activated CDC42 kinase 1; ACK-1; tyrosine kinase non-receptor protein 2 (TNK2, ACK1)
• Bruton tyrosine kinase; agammaglobulinemia tyrosine kinase; ATK; B-cell progenitor tyrosine kinase (BPK, BTK, AGMX1)
• c-src kinase (CSK) or protein tyrosine kinase CYL
• dual specificity protein kinase CLK4; CDC-like kinase 4 (CLK4)
• dual specificity protein kinase TTK; phosphotyrosine picked threonine-protein kinase; PYT (TTK, MPS1, MPS1L1)
• dual-specificity tyrosine-phosphorylation regulated kinase
• dual-specificity tyrosine-phosphorylation regulated kinase 1A (protein kinase minibrain homolog, MNBH, HP86, dual specificity YAK1-related kinase, Dyrk1A)
• focal adhesion kinase (FAK)
• fps protein or fes protein
• IL2-inducible T-cell kinase
• insulin receptor beta (INSRA)
• Janus kinase (JAK)
• membrane-associated tyrosine-& threonine-specific cdc2-inhibitory kinase; Myt1 kinase (PKMYT1, MYT1)
• mitogen activated protein kinase kinase (MAP2K), MAPK/ERK kinase (MEK)
• mitogen-activated protein kinase kinase kinase 10 (MAP3K10, mixed lineage kinase [MLK] 2, MLK2, MST)
• mitogen-activated protein kinase kinase kinase 9 (MAP3K9, mixed lineage kinase [MLK] 1, MLK1, PRKE1)
• nim1 kinase
• non-receptor tyrosine-protein kinase TNK1; CD38 negative kinase 1 (TNK1)
• p21rho G-associated kinase [ACK] or CDC42Hs-associated kinase
• p75 liver tyrosine kinase
• protein kinase CLK (cdc-like kinase)
• protein tyrosine kinase 6; breast tumor kinase; tyrosine protein kinase BRK (PTK6 BRK)
• serine/threonine protein kinase ULK2; Unc-51-like kinase 2 (ULK2, KIAA0623)
• spleen tyrosine kinase (Syk)
• src proto-oncogene protein family
• Tec tyrosine kinase (TEC, PSCTK4)
• thymic p40 tyrosine kinase
• titin (connectin, rhabdomyosarcoma antigen MU-RMS-40.14, TTN)
• tubulin-tyrosine ligase (TTL)
• TXK tyrosine kinase (TXK, PTK4)
• tyrosine kinase CTK; protein kinase HYL; hematopoietic consensus tyrosine-lacking kinase; protein kinase MATK; megakayrocyte-associated protein kinase (MATK, CTK, HYL)
• tyrosine kinase receptor (RTK)
• tyrosine protein kinase 7; colon carcinoma kinase 4; CCK-4; protein tyrosine kinase 7; pseudo tyrosine kinase receptor 7; tyrosine protein kinase-like 7 (PTK7, CCK4)
• tyrosine-protein kinase FRK; FYN-related kinase; nuclear tyrosine protein kinase RAK (FRK, PTK5, RAK)
• tyrosine-protein kinase SgK223 (Sugen kinase 223, SGK223)
• tyrosine-protein kinase SgK269 (PEAK1)
• tyrosine-protein kinase Srms (SRMS, C20orf148)
• tyrosine-protein kinase STYK1; novel oncogene with kinase domain; protein PK-unique; serine/threonine/tyrosine kinase 1 (STYK1, NOK)
• wee1 proto-oncogene protein
• Wee1-like protein kinase 1B; Wee1B kinase (WEE1B, WEE2)
• X-linked bone marrow [BMX] tyrosine kinase; epithelial & endothelial tyrosine kinase (BMX, ETK, NTK38)
• Zap-70 tyrosine kinase; zeta-associated protein 70 kD; Syk-related tyrosine kinase (ZAP70, SRK)

Additional terms

• Tyrosine phosphorylation site