c-src kinase (CSK) or protein tyrosine kinase CYL

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^[1]^[2]

Function

c-src kinase phosphorylates c-src protein (p60 c-src) at Tyr-527, a negative regulatory site
Csk associates with paxillin & the focal adhesion kinase (FAK) through binding of its SH2 domain to Tyr-phosphate within paxillin^[2]

More general terms

tyrosine kinase (protein tyrosine kinase, PTK)

References

↑ Nada S, Okada M, MacAuley A, Cooper JA, Nakagawa H. Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src. Nature. 1991 May 2;351(6321):69-72. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1709258
↑ ^2.0 ^2.1 Clark EA & Brugge JS Integrins and signal transduction pathways: the road taken. Science 268:233 1995 PMID: https://www.ncbi.nlm.nih.gov/pubmed/7716514

Database

UniProt: http://www.uniprot.org/uniprot/P41240.html
OMIM: https://mirror.omim.org/entry/124095
Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1445

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