Tec tyrosine kinase (TEC, PSCTK4)
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Function
Cofactor: binds 1 Zn+2 per subunit (putative)
Structure
- belongs to the protein kinase superfamily, Tyr protein kinase family, TEC subfamily
- contains 1 Btk-type Zn+2 finger
- contains 1 PH domain
- contains 1 protein kinase domain
- contains 1 SH2 domain
- contains 1 SH3 domain
Compartment
cytoplasm (probable)
Expression
- hematopoietic cell lines including myeloid, B-cells, & T-cell lineages
Notes
It is uncertain whether Met-1 is the initiator
More general terms
Component of
References
- ↑ Pawson T Protein modules and signalling networks Nature 373:573 1995 PMID: https://www.ncbi.nlm.nih.gov/pubmed/7531822
- ↑ Sato K, Mano H, Ariyama T, Inazawa J, Yazaki Y, Hirai H. Molecular cloning and analysis of the human Tec protein- tyrosine kinase. Leukemia. 1994 Oct;8(10):1663-72. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7934162
- ↑ UniProt http://www.uniprot.org/uniprot/P42680.html