src proto-oncogene protein family
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Function
- may associate with cadherin/catenin complexes
- may be directly stimulated by cytokine receptors
Structure
- kinase domain is SH1 domin or src homology-1 domain
More general terms
- tyrosine kinase (protein tyrosine kinase, PTK)
- myristoylated protein
- proto oncogene protein
- SH2 domain-containing protein
More specific terms
- blk proto-oncogene protein; tyrosine-protein kinase BLK; B lymphocyte kinase; p55-BLK (BLK)
- fgr proto-oncogene protein
- hck protein; tyrosine-protein kinase HCK; p59-HCK/p60-HCK; hemopoietic cell kinase (HCK)
- lck proto-oncogene protein
- Lyn proto-oncogene protein (tyrosine-protein kinase Lyn, LYN)
- proto-oncogene tyrosine-protein kinase Fyn; p59-Fyn; protooncogene syn; SLK (FYN)
- src proto-oncogene protein
- yes protein
References
- ↑ Matsuda M, Mayer BJ, Fukui Y, Hanafusa H. Binding of transforming protein, P47gag-crk, to a broad range of phosphotyrosine-containing proteins. Science. 1990 Jun 22;248(4962):1537-9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1694307
- ↑ Einspahr et al, Protein tyrosine phosphorylation and p56lck modification in IL-2 or phorbol ester-activated human natural killer cells. J Immunol 1990 Sep 1;145(5):1490-7 PMID: https://www.ncbi.nlm.nih.gov/pubmed/1696599
- ↑ Bolen JB, Rowley RB, Spana C, Tsygankov AY. The Src family of tyrosine protein kinases in hemopoietic signal transduction. FASEB J. 1992 Dec;6(15):3403-9. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1281458