cadherin
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Function
- Ca+2-dependent cell adhesion proteins
- control of adhesion specificities through homophilic binding interactions
- thus, cadherins bind to themselves as receptor & ligand
- role in sorting of heterogeneous cell types
- cadherin/catenin complexes associate with the cytoskeleton & src family of tyrosine kinases
More general terms
More specific terms
- cadherin-2; neural cadherin; N-cadherin; CDw325; CD325 (CDH2, CDHN, NCAD)
- cadherin-3; placental cadherin; P-cadherin (CDH3, CDHP)
- cadherin-4; retinal cadherin; R-cadherin; R-CAD (CDH4)
- cadherin-5 (CD144, vascular endothelial cadherin, VE-cadherin, 74B antigen, CDH5)
- cadherin-6 (kidney cadherin, K-cadherin, CDH6)
- cadherin-7 (CDH7, CDH7L1)
- cadherin-8
- cadherin-9 (CDH9)
- cadherin-10; T2-cadherin (CDH10)
- cadherin-11; osteoblast cadherin; OB-cadherin; OSF-4 (CDH11)
- cadherin-12; brain cadherin; BR-cadherin; neural type cadherin 2; N-cadherin 2 (CDH12)
- cadherin-13; Truncated cadherin; T-cadherin; T-cad; heart cadherin; H-cadherin; P105 (CDH13, CDHH)
- cadherin-15; muscle cadherin; M-cadherin; cadherin-14 (CDH15 CDH14 CDH3)
- cadherin-16; kidney-specific cadherin; Ksp-cadherin (CDH16)
- cadherin-17; liver-intestine cadherin; LI-cadherin; intestinal peptide-associated transporter HPT-1 (CDH17)
- cadherin-18; cadherin-14 (CDH18, CDH14)
- cadherin-19 (CDH19 CDH7L2 UNQ478/PRO941)
- cadherin-20 (CDH20, CDH7L3)
- cadherin-22; pituitary & brain cadherin; PB-cadherin (CDH22, C20orf25)
- cadherin-23; otocadherin (CDH23, KIAA1774, KIAA1812, UNQ1894/PRO4340)
- cadherin-24 (CDH24, CDH11L, UNQ2834/PRO34009)
- cadherin-like protein 26; cadherin-like protein VR20 (CDH26)
- Cadherin-like protein 28 (CDH28, CDHR3)
- cadherin-like protein UNQ9392/PRO34300 (CDHR4)
- CD324; E-cadherin; cadherin-1; epithelial cadherin; uvomorulin; CAM 120/80 (CDH1, CDHE, UVO)
Additional terms
- catenin
- protocadherin (PCDH)
- protocadherin fat 1; cadherin-related tumor suppressor homolog; protein fat homolog; cadherin family member 7 (FAT1, CDHF7, FAT)
- protocadherin fat 2; hfat2; multiple epidermal growth factor-like domains protein 1; multiple EGF-like domains protein 1; cadherin family member 8 (FAT2, CDHF8, KIAA0811, MEGF1)
References
- ↑ Takeichi M. Cadherin cell adhesion receptors as a morphogenetic regulator. Science. 1991 Mar 22;251(5000):1451-5. Review. PMID: https://pubmed.ncbi.nlm.nih.gov/2006419
- ↑ Walsh FS et al N-cadherin gene maps to human chromosome 18 and is not linked to the E-cadherin gene. J Neurochem. 1990 Sep;55(3):805-12. PMID: https://pubmed.ncbi.nlm.nih.gov/2384753