CD144 (cadherin-5, vascular endothelial cadherin, VE-cadherin, 74B antigen, CDH5)

Function

• cadherin
• may play role in endothelial cell function through control of thecohesion & organization of the intercellular junctions
• associates with alpha-catenin forming a link to the cytoskeleton

Structure

contains 5 cadherin domains

Compartment

• cell junction, cell membrane
• found at cell-cell boundaries & probably at cell-matrix boundaries

Expression

endothelial tissues & brain

More general terms

• cadherin
• glycoprotein
• phosphoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1003
• OMIM: https://mirror.omim.org/entry/601120
• UniProt: http://www.uniprot.org/uniprot/P33151.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1003