protocadherin fat 1; cadherin-related tumor suppressor homolog; protein fat homolog; cadherin family member 7 (FAT1, CDHF7, FAT)

Function

• could function as a cell-adhesion protein
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• contains 34 cadherin domains
• contains 5 EGF-like domains
• contains 1 laminin G-like domain

Compartment

• cell membrane; single-pass type 1 membrane protein (putative)

Expression

• expressed in many epithelial cells, ome endothelial cells & smooth muscle cells

More general terms

• glycoprotein
• adhesion receptor
• phosphoprotein

Additional terms

• cadherin
• protocadherin fat 2; hfat2; multiple epidermal growth factor-like domains protein 1; multiple EGF-like domains protein 1; cadherin family member 8 (FAT2, CDHF8, KIAA0811, MEGF1)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2195
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2195
• OMIM: https://mirror.omim.org/entry/600976
• UniProt: http://www.uniprot.org/uniprot/Q14517.html