nim1 kinase

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Introduction

Phosphorylates & inhibits c-wee1 kinase. Higher eukaryotic homologs of nim1 have not been identified

↑ Gautier J, Solomon MJ, Booher RN, Bazan JF, Kirschner MW. cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2. Cell. 1991 Oct 4;67(1):197-211. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1913817
↑ Parker LL, Walter SA, Young PG, Piwnica-Worms H. Phosphorylation and inactivation of the mitotic inhibitor Wee1 by the nim1/cdr1 kinase. Nature. 1993 Jun 24;363(6431):736-8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8515817
↑ Wu L, Russell P. Nim1 kinase promotes mitosis by inactivating Wee1 tyrosine kinase. Nature. 1993 Jun 24;363(6431):738-41. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8515818
↑ Morgan DO. Principles of CDK regulation. Nature. 1995 Mar 9;374(6518):131-4. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7877684