histone acetyltransferase MYST1; MYST protein 1; YBF2/SAS3; SAS2 & TIP60 protein 1; hMOF (MYST1, KAT8, MOF, PP7073)

Function

• histone acetyltransferase
• role in transcriptional activation (putative)
• may influence the function of ATM
• interacts with the chromodomain of MORF4L1/MRG15
• interacts with ATM through the chromodomain.

Acetyl-CoA + histone <--> CoA + acetylhistone

Structure

• belongs to the MYST (SAS/MOZ) family
• contains 1 C2HC-type zinc finger
• contains 1 chromo domain

Compartment

nucleus

Alternative splicing

named isoforms=3

More general terms

• histone acetyltransferase
• zinc finger protein
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9H7Z6.html