thyroid receptor-interacting protein 1; 26S proteasome regulatory subunit 8 (TRIP1, ATPase-5, PSMC5, SUG1)

Function

• component of 26S protease
• interacts, in vitro, with the thyroid hormone receptor (T3-dependent) & with retinoid X receptor (RXR) (putative)
• interacts with NDC80
• interacts with PAAF1

Structure

• belongs to the AAA ATPase family
• homologous to the yeast transcriptional mediator Sug1

Compartment

cytoplasm (putative), nucleus (putative)

Expression

• ubiquitously expressed

More general terms

• transcription factor (TF)
• thyroid hormone receptor interacting protein (TRIP)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5705
• OMIM: https://mirror.omim.org/entry/601681
• UniProt: http://www.uniprot.org/uniprot/P62195.html