ventral anterior homeobox 2 (VAX2)

Function

• role in eye development, in particular, in specification of the ventral optic vesicle
• may regulate axial polarization in the retina

Structure

• belongs to the EMX homeobox family
• contains 1 homeobox DNA-binding domain

Compartment

nucleus (probable)

Expression

• in the embryo, expressed in the ventral part of the optic vesicles at 7 weeks

More general terms

• homeobox protein
• transcription factor (TF)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=25806
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:25806
• OMIM: https://mirror.omim.org/entry/604295
• UniProt: http://www.uniprot.org/uniprot/Q9UIW0.html