apolipoprotein A1 regulatory protein-1; transcription factor COUP 2; COUP-TF2; nuclear receptor subfamily 2 group F member 2; apolipoprotein AI regulatory protein 1 (ARP1, TFCOUP2, ARP-1, NR2F2)

Function

• regulation of the apolipoprotein A1 gene transcription
• binds to DNA site A
• interacts with SQSTM1 (putative)
• binds DNA as a homodimer

Structure

• belongs to the nuclear hormone receptor family, NR2 subfamily
• contains 1 nuclear receptor DNA-binding domain

Compartment

nucleus

Expression

found in all tissues

More general terms

• transcription factor (TF)
• DNA-binding protein
• zinc finger protein

Database

• UniProt: http://www.uniprot.org/uniprot/P24468.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7026
• OMIM: https://mirror.omim.org/entry/107773