death-associated transcription factor 1; death-inducer obliterator 1 (DATF1, DIO-1, C20orf158, KIAA0333)

Function

• transcription factor (putative)
• weakly pro-apoptotic when overexpressed
• tumor suppressor

Compartment

• cytoplasm, nucleus
• translocates to the nucleus after pro-apoptotic stimuli

Alternative splicing

named isoforms=4

Expression

ubiquitously expressed

Pathology

• defects in DATF1 may be a cause of myeloid neoplasms

More general terms

• transcription factor (TF)
• phosphoprotein
• zinc finger protein

Database

• OMIM: https://mirror.omim.org/entry/604140
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=11083
• UniProt: http://www.uniprot.org/uniprot/Q9BTC0.html