One cut domain family member 2; hepatocyte nuclear factor 6-beta; HNF-6-beta; one cut homeobox 2; transcription factor ONECUT-2; OC-2 (ONECUT2, HNF6B)

Function

• transcriptional activator
• activates the transcription of a number of liver genes such as HNF3B

Structure

• belongs to the CUT homeobox family
• contains 1 CUT DNA-binding domain
• contains 1 homeobox DNA-binding domain

Compartment

nucleus

Notes

• uncertain whether Met-1 or Met-20 is the initiator

More general terms

• transcription factor (TF)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9480
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9480
• OMIM: https://mirror.omim.org/entry/604894
• UniProt: http://www.uniprot.org/uniprot/O95948.html