forkhead box protein A2; hepatocyte nuclear factor 3-beta; HNF-3B (FOXA2)

Function

• transcription activator for a number of liver genes including AFP, albumin, tyrosine aminotransferase, PEPCK
• interacts with cis-acting regulatory regions of these genes
• binds TLE1

Structure

contains 1 fork-head DNA-binding domain

Compartment

nucleus

More general terms

• forkhead family transcription factor

Database

• OMIM: https://mirror.omim.org/entry/600288
• UniProt: http://www.uniprot.org/uniprot/Q9Y261.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3170