p53 family protein

Function

• p63 & p73 have essential roles in development
• p53, p63 & p73 affect transcriptional activity & apoptosis
• p53 has role in tumor suppression, is activated by cellular stress signals, inactivated by oncogenic viruses & degraded by mdm2.

More general terms

• DNA-binding protein
• transcription factor (TF)
• oligomerizing protein

More specific terms

• cellular tumor antigen p53; tumor suppressor p53, phosphoprotein p53; antigen NY-CO-13 (TP53, p53)
• p51 protein
• p63 protein; p53 homolog p63; tumor protein p73-like; p73L; TP63; p51; p40; keratinocyte transcription factor KET; chronic ulcerative stomatitis protein (CUSP, TP73L, KET, p63, P73H)
• tumor protein p73; p53-like transcription factor; p53-related protein (TP73, p73)