mediator of RNA polymerase II transcription subunit 7; hMED7; activator-recruited cofactor 34 kD component; ARC34; cofactor required for Sp1 transcriptional activation subunit 9; CRSP complex subunit 9; mediator complex subunit 7; RNA polymerase transcriptional regulation mediator subunit 7 homolog; transcriptional coactivator CRSP33 (MED7 ARC34 CRSP9)

Function

• component of the mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase 2- dependent genes.
• constitutively sumoylated

Structure

• belongs to the mediator complex subunit 7 family

Compartment

nucleus

More general terms

• transcription factor (TF)
• phosphoprotein

Component of

• activator-recruited cofactor (ARC)/DRIP
• mediator complex (mediator of RNA polymerase 2 transcription)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9443
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9443
• OMIM: https://mirror.omim.org/entry/605045
• UniProt: http://www.uniprot.org/uniprot/O43513.html