transcription factor Sp7 (zinc finger protein osterix, SP7, OSX)

Function

• transcriptional activator essential for osteoblast differentiation
• binds to Sp1 & EKLF consensus sequences & to other G/C-rich sequence

Structure

• belongs to the Sp1 C2H2-type zinc-finger protein family
• contains 3 C2H2-type zinc fingers

Compartment

nucleus

More general terms

• transcription factor (TF)
• C2H2 type zinc finger protein

Database

• OMIM: https://mirror.omim.org/entry/606633
• UniProt: http://www.uniprot.org/uniprot/Q8TDD2.html