sry-box-8 protein; transcription factor sox-8 (sox8)

Function

• may play a role in central nervous system, limb & facial development
• may be involved in male sex determination
• binds the consensus motif 5'-[AT][AT]CAA[AT]G-3' (putative)

Structure

contains 1 HMG box DNA-binding domain

Compartment

nucleus (putative)

More general terms

• sox protein
• transcription factor (TF)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3081
• UniProt: http://www.uniprot.org/uniprot/P57073.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=30812